Ask a doctor before use if you have heart disease, high blood pressure, thyroid disease, diabetes, difficulty in urination due to enlargement of the prostate gland. Ask a doctor or pharmacist before use if you are presently taking a prescription drug for high blood pressure or depression. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. If swallowed, get medical help or contact a poison control center right away. (1-800-222-1222). Stop use and ask a doctor if bleeding occurs, condition worsens or does not improve within 7 days. When using this product do not exceed the recommended daily dosage unless directed by a doctor. For rectal use only.