No refrigeration required. Store in a cool dry place.
Dissolve contents of 1 packet into 8-16 fluid ounces of any liquid or food (<75 degrees F). Consume within 12 hours of mixing, with or without food.
Recommended use (all ages): consume 1 packet every other day to maintain healthy intestinal balance. Consume 1 or more packets daily, if desired or needed to address more acute health concerns.
Note: during first days of use, as bacteria in the digestive tract rebalance, temporary bloating, digestive gurgling and gas may occur, but normally subsides within one week.